The UK has approved the Wegovy pill, a new weight-loss medication that could revolutionize how people manage their weight. Find out how it works and who can benefit.

The UK has taken a significant step in the fight against obesity with the approval of the Wegovy pill a new form of the popular weight-loss medication previously available only as an injection. This development has been met with enthusiasm by those struggling with weight management, offering a more convenient alternative to the weekly injections.
The pill contains semaglutide the same active ingredient as the Wegovy injection, which works by mimicking a hormone called GLP-1 to suppress appetite. Early reports from the US, where the pill has been available since January, suggest remarkable results, with users experiencing significant weight loss and improved energy levels.
Patient experiences and early results
Patients in the US have shared their success stories with the Wegovy pill. Rebecca Walker, a 47-year-old graphic designer from Nevada, lost over 15lb in just two months. She had previously struggled with weight gain after menopause and found the pill to be a life-changing solution.
‘I quickly started to notice a difference,’ she said. ‘I started losing weight, I could fit into my clothes again, and my energy went back up. I’m running again now.’
David Clarke, a 40-year-old communications worker from New York, also reported positive results. After just three weeks on the pill, he had lost 5lb and noticed a significant reduction in food cravings. ‘Since starting the pill, the food noise inside my head has really quietened,’ he shared. ‘I used to think about food all the time—especially cakes, candy, cookies, and ice cream. The pill has shut a lot of that down.’
Availability and cost considerations
The Wegovy pill is expected to be rolled out at private clinics in the UK over the next few weeks. However, it will not be available on the NHS initially. The daily tablet will be available to patients with a BMI of 30 or above or those with a BMI between 27 and 30 who have a weight-related condition such as heart disease, high blood pressure, or sleep apnea.
Experts predict that the pill will be more affordable than the injections. In the US, a month’s supply of the highest dose costs about £225, compared to around £260 for the injections. However, prices in the UK may vary depending on the provider. Some online pharmacies have already started listing prices, with Chemist4U offering the 25mg Wegovy pill for £199 a month, the same price as the injections.
The cost of the injections was a significant barrier for many. Rebecca Walker mentioned that the price of the injections was too high for her, making the pill a more accessible option. ‘I can actually afford to stick with the pills,’ she said.
Effectiveness and side effects
Studies suggest that the Wegovy pill is slightly less effective than the injections, with patients losing about 14% of their body weight compared to 15% with the injections. However, experts note that the difference is minimal and that the pill can be just as effective once patients reach the highest dose.
The pill has broadly the same side effects as the injections, including nausea, vomiting, diarrhea, constipation, bloating, and heartburn. These symptoms typically occur when patients first start taking the drug or when their dose is increased. In rare cases, the pill can trigger pancreatitis, a serious condition that requires immediate medical attention.
Patients have reported that the side effects are generally mild and manageable. Rebecca Walker experienced an upset stomach for the first few days but found it to be nothing to worry about. David Clarke mentioned that he follows a simple routine to ensure the pill is effective: taking it first thing in the morning and setting a 30-minute timer before eating breakfast.
Experts emphasize the importance of following the correct steps to maximize the pill’s effectiveness. According to Novo Nordisk, the Wegovy pill must be taken with a small glass of water after an eight-hour fast, and patients must avoid eating for a further 30 minutes while it is absorbed. ‘The drug will only work if people follow these instructions,’ said Professor David Strain, a weight-loss expert at the University of Exeter.
For those looking to ‘supercharge’ their weight loss, experts recommend improving diet and lifestyle habits. Dr. Madusha Peiris, a weight-loss expert at Queen Mary University of London, suggests focusing on protein and fiber-rich foods to maintain muscle and reduce overeating. ‘Being on these drugs is the ideal time to overhaul your diet, when you have more control over your appetite,’ she said.
Patience is also key. David Clarke noted that the pill didn’t instantly fix his relationship with food but that over time, his cravings faded. ‘For the first time, I feel like I have a normal appetite,’ he shared. ‘It’s such a relief not to be thinking about food all the time—but I know I still need to stick with it and make healthy choices.’
