New research reveals a simple test that may predict lifespan by measuring intrinsic capacity.

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It may sound like a plot twist from a science fiction novel, but researchers from the US and France have made a groundbreaking discovery. They’ve developed a test that shows promise in predicting how long we might live. This innovative approach revolves around measuring intrinsic capacity (IC), which encompasses all the physical and mental abilities we possess, from walking to memory.
Intrinsic capacity: the key to healthy aging
For decades, intrinsic capacity has been heralded as a reliable indicator of healthy aging. Traditionally, assessing IC has been a complex and expensive endeavor, requiring extensive evaluations of physical health. However, this new research suggests that a straightforward saliva or blood test could effectively gauge IC by analyzing DNA methylation patterns.
These chemical markers play a crucial role in regulating gene activity and can provide insights into an individual’s biological age.
The study: a decade of research
Over the course of ten years, researchers closely monitored more than 1,000 adults, aged between 20 and 102. Participants underwent evaluations based on five critical age-related risk factors: cognitive abilities, mobility, vision and hearing, vitality, and mental well-being. The findings were striking; those with elevated IC scores tended to live an average of 5.5 years longer than their peers. Individuals with the highest scores boasted superior lung function, quicker walking speeds, and a greater sense of well-being.
Linking diet to biological aging
Moreover, the researchers also explored how diet influences biological aging. They discovered that individuals who consumed oily fish such as salmon and mackerel while limiting sugar intake tended to have higher IC scores. In their publication in the journal *Nature Aging*, the team noted, ‘We found that individuals with higher IC consumed more beer and dark meat, along with fish varieties like mackerel and sardines, while taking fewer calcium supplements.’ This suggests that a diet rich in omega-3 fatty acids may play a vital role in promoting longevity.
Expert opinions on the findings
Professor Thomas Holland from the RUSH Institute for Healthy Aging, who was not part of the study, emphasized the significance of this research. He declared, ‘A blood or saliva-based test for intrinsic capacity is a very promising tool in aging science.’ Holland pointed out that this test does not merely indicate one’s age but rather assesses the quality of one’s aging process, paving the way for targeted interventions to prevent health issues.
Maintaining a healthy lifestyle
Healthcare professionals like Dr. Tunç Tiryaki, a board-certified plastic surgeon, echo similar sentiments regarding lifestyle choices. He highlights the importance of regular exercise, balanced nutrition, and social engagement in maintaining both physical and cognitive health. He stated, ‘Staying active and fostering social connections can significantly mitigate the risks associated with age-related diseases.’
A future where lifespan prediction is possible
This groundbreaking research opens new avenues for understanding aging. With the ability to predict lifespan through a simple test, the potential for early interventions becomes a reality. As scientists continue to unravel the complexities of aging, we might soon have the tools needed to enhance our health and longevity.