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DIY Mounjaro microdosing: the controversial weight loss method

A 40-year-old NHS receptionist shares her weight loss success using a controversial DIY Mounjaro hack, but experts warn of the significant risks involved.

The recent trend of Mounjaro microdosing has gained significant attention on social media, particularly among those sharing their weight loss journeys. This unconventional method raises questions about its safety and effectiveness. One notable story is that of Siobhan Jackson, a 40-year-old NHS receptionist who reportedly lost four stone using this approach.

This article examines her experience and expert opinions on the practice.

Siobhan’s Weight Loss Journey

Siobhan Jackson, from Kirby-in-Ashfield, Nottinghamshire, experienced a remarkable transformation, dropping from 14 stone 1 lb (size 20) to just under 10 stone (size 10–12) in 11 months.

Her method involved ‘microdosing,’ which entails administering smaller and more frequent doses of Mounjaro than typically prescribed.

Jackson acknowledged that her approach diverged from medical guidelines, stating, “In my experience, people are not taking it as prescribed. I’m not the only one—lots of people are doing this.” This raises concerns about the potential risks associated with such practices.

Initially, Siobhan sought Mounjaro due to struggles with weight and dangerously high blood pressure, which peaked at 170/140. Overwhelmed by her situation and relying on a mix of medications and unhealthy eating habits, she was motivated to change after witnessing the positive effects of weight loss on her health and the success of patients at her workplace.

The DIY Mounjaro Hack

After purchasing her first Mounjaro pen online for approximately £100, Siobhan experienced immediate appetite suppression. “I wasn’t hungry at all,” she said, recalling that she sometimes did not eat until 2 PM. This newfound control was transformative for her. However, she later began to adjust her dosage after discussions in online groups, reducing her intake from 7.5mg to 6.25mg and administering 3.125mg twice weekly.

“For me, microdosing worked really well,” she explained. “I didn’t want to be losing half a stone in a week.” As her weight loss stabilized, she expressed a desire to eventually discontinue microdosing. This situation prompts a critical inquiry: what are the implications of self-managing health interventions?

Experts Weigh In on the Risks

While Siobhan expresses confidence in her method, health professionals caution against the potential dangers of microdosing. Dr. Max Pemberton, an NHS psychiatrist, warns that improper dosing can lead to serious health risks, including inadequate or excessive medication that may create a false sense of security. “Absolutely no reputable prescriber would endorse this behavior,” he stated, emphasizing the health risks involved.

Furthermore, Professor Alex Miras, an endocrinologist, pointed out the risks of serious side effects from overdosing and the possibility of life-threatening infections from improper use of the pens. “Don’t take the risk,” he advised. The Medicines and Healthcare Products Regulatory Agency (MHRA) also stresses the importance of adhering strictly to healthcare provider guidelines to prevent injury.

Despite these warnings, Siobhan expresses gratitude for the support from microdosing communities, which provided her with comfort during her weight loss journey. “Had it not been for the groups, I wouldn’t have been as comfortable microdosing,” she reflected. “But it worked for me—and I know I’m not the only one.”

This growing trend sparks essential dialogue about the balance between individual choice and safety in weight loss practices. What are your thoughts on this issue? Is the potential risk justifiable in pursuit of weight loss? Let’s discuss.


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