A heartbreaking incident involving an unregulated weight-loss injection compels a family to champion stricter regulations on unlicensed pharmaceuticals.

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In a tragic incident highlighting the perils of unregulated weight-loss treatments, the family of Karen McGonigal, a 53-year-old mother from Salford, Greater Manchester, is urging for immediate action. Karen died in May after receiving an illegal injection of a drug marketed for weight loss.
Her story emphasizes the urgent need for regulatory measures against so-called ‘skinny jabs’ that are easily accessible on the black market.
The quest for weight loss
Struggling with her weight and mental health challenges following a difficult relationship, Karen sought assistance from her general practitioner.
After undergoing tests to assess her eligibility for NHS weight-loss injections, she was informed that she did not meet the criteria for the treatment. Desperate to regain her confidence, she turned to advice from friends who suggested that weight-loss injections could be acquired at a nearby beauty salon.
Unlicensed treatments and their consequences
At a salon offering injections for a mere £20, Karen thought she was receiving Mounjaro, a licensed medication designed for weight loss and diabetes management. However, she was unknowingly injected with semaglutide, a drug not approved for use outside specialized medical settings. Reports reveal that these injections were administered without following proper medical protocols, lacking essential sanitation and preparation. Karen’s daughter, Ffion, described how the beautician would escort her mother into a back room, completing the procedure in just a few minutes.
Health implications and tragic outcome
Initially, Karen experienced weight loss. However, just four days after her final injection, she began suffering from severe stomach pain and respiratory issues. Her daughter, Ffion, who lived with her, noticed alarming symptoms, including a change in her mother’s complexion, and quickly called for an ambulance. Tragically, after two days in intensive care, the family learned from medical staff that there was nothing more they could do to save her.
Legal repercussions and government response
Following the incident, Greater Manchester Police arrested two individuals: one on suspicion of manslaughter and the other for supplying a controlled substance. Health Secretary Wes Streeting offered condolences to Karen’s family and highlighted the government’s dedication to tackling the issue of black market drugs. He urged individuals to consult licensed medical professionals before pursuing any weight-loss treatments and encouraged the reporting of illegal sales.
Broader implications and the need for change
The tragic death of Karen has driven her family to campaign for stricter regulations on unlicensed weight-loss injections. Abbie McGonigal, one of Karen’s daughters, expressed concern, stating, “There are numerous people out there injecting others with these dangerous substances. More needs to be done to hold these individuals accountable.” This warning underscores the potential risks associated with unregulated treatments aimed at rapid weight loss, highlighting that the consequences can be severe.
NHS England has emphasized that medications such as semaglutide should only be provided through authorized weight management services. These medications are not appropriate for everyone, particularly pregnant or breastfeeding women, or those with specific medical conditions. The family aims to use their experience to prevent others from facing a similar tragedy.
The tragic case of Karen McGonigal underscores the serious risks associated with unregulated weight-loss drugs. Her family’s efforts to raise awareness and push for stricter regulations emphasize the urgent need to safeguard individuals from the dangers of the black market.




