A comprehensive analysis of 17 trials involving over 20,000 participants concludes that current anti-amyloid monoclonal antibodies produce minimal cognitive benefit while raising safety and cost concerns.
Iran has signalled it will maintain restrictions on the Strait of Hormuz while the US blockade of Iranian ports continues, even as mediators press for fresh talks before the ceasefire ends
Tehran says the strategic Strait of Hormuz will remain closed until Washington ends its blockade of Iranian ports, even as talks and regional diplomacy continue
A newly appointed parliamentary engagement officer resigned following online criticism, prompting questions about who can represent health causes and how charities choose advocates
A renewed controversy over Peter Mandelson’s failed security vetting has reopened scrutiny of Keir Starmer’s leadership and raised questions about ministerial responsibility
England extended their World Cup qualifying run with a win over Spain at Wembley on 14 April 2026, a match that combined personal landmarks and fresh selection storylines
A street altercation in the Sackville Street area resulted in injuries to two officers and the arrest of a male in his late teens; police continue enquiries and seek public help
Transport for London and the RMT remain at odds over a proposed four-day working week, prompting a series of 24-hour strikes that will affect key Tube lines and push passengers to find alternatives
Video shows police confiscating and destroying footballs at Al-Aqsa in occupied East Jerusalem; mosque officials describe the move as part of continuing restrictions
Coventry’s late equaliser restores top‑flight status and reframes the Premier League battle as Arsenal and Manchester City face a critical fixture while Manchester United monitor Marcus Rashford’s situation
SEPA and local partners are investigating a pollution event on the Burn of Carron after white discolouration and dead aquatic life were reported; anyone with information is asked to contact SEPA
A major review finds large disparities in access to educational psychologists, an undercounted workforce, and a clear case for expanding training and local provision to protect SEND reform
Downing Street published a readout that the prime minister did not know about a decision to grant Developed Vetting to Peter Mandelson until a recent meeting, but scrutiny has shifted to senior civil servants and the handling of documents
Residents gathered in Epsom to demand more information after an alleged attack near Epsom Methodist Church, while police urge calm and continue inquiries
SEPA officers are investigating a pollution event on the Burn of Carron after reports of white discolouration, a turpentine-like odour and dead fish; the burn and the River Spey are now clear while assessments continue
Sources say Arsenal staged a meeting at the training ground where a real fire was lit following Mikel Arteta’s unusual press conference remarks as he tries to rally his players
An animal rights protester entered a Michelin-starred restaurant in Weymouth, removed a lobster kept for educational purposes and released it into the harbour; the court ruled the act was misguided and handed down a conditional discharge